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1

Memory Loss and the Onset of Alzheimer’s Disease Could Be Under the Control of Extracellular Heat Shock Proteins

Arispe, Nelson, De Maio, Antonio

Journal:

Journal of Alzheimer's Disease

Year:

2018

Language:

english

File:

PDF, 479 KB

english, 2018

2

Annexin 5 and apolipoprotein E2 protect against Alzheimer’s amyloid-β-peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site

George Lee, Harvey B Pollard, Nelson Arispe

Journal:

Year:

2002

Language:

english

File:

PDF, 513 KB

english, 2002

3

Bacterial Hsp70 (DnaK) and mammalian Hsp70 interact differently with lipid membranes

Lopez, Victor, Cauvi, David M., Arispe, Nelson, De Maio, Antonio

Journal:

Cell Stress and Chaperones

Year:

2016

Language:

english

File:

PDF, 492 KB

english, 2016

4

The Interaction of Hsp70 with Phosphatidylserine Membranes is Mediated by a Highly Positive Region of the Molecule

Lopez, Victor, Cauvi, David M., Arispe, Nelson, De Maio, Antonio

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 44 KB

english, 2015

5

Nitrendipine, an antihypertensive alpha calcium channel blocker, is cytotoxic to neuroblastoma cells

Rivera, Isabel, Cauvi, David M., Arispe, Nelson, De Maio, Antonio

Journal:

Molecular & Cellular Toxicology

Year:

2019

File:

PDF, 584 KB

2019

6

Chronic Cytosolic Calcium Changes Induced by Alzheimer's Peptides Aβ Allows for Sorting of Aβ-Resistant Cell Subpopulations

Lin, Ho-pi, Knight, Brandon, Arispe, Nelson J.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

7

A new drug target for treating Alzheimer's disease (AD): Structural images and models of Abeta-42 channels and their blockade by small molecule drugs, synthetic peptides, and metal cations

H. Robert Guy, Yinon Shafrir, Stewart R. Durell, Nelson Arispe, Harvey B. Pollard

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 45 KB

english, 2009

8

Intrinsic Anion Channel Activity of the Recombinant First Nucleotide Binding Fold Domain of the Cystic Fibrosis Transmembrane Regulator Protein

Nelson Arispe, Eduardo Rojas, John Hartman, Eric J. Sorscher and Harvey B. Pollard

Journal:

Proceedings of the National Academy of Sciences

Year:

1992

Language:

english

File:

PDF, 1.32 MB

english, 1992

9

Lipid Interaction Differentiates the Constitutive and Stress-Induced Heat Shock Proteins Hsc70 and Hsp70

Nelson Arispe, Michael Doh and Antonio De Maio

Journal:

Cell Stress and Chaperones

Year:

2002

Language:

english

File:

PDF, 528 KB

english, 2002

10

Fluorescent Analysis of the Cell-Selective Alzheimer's Disease A β Peptide Surface Membrane Binding: Influence of Membrane Components

Simakova, Olga, Arispe, Nelson J.

Journal:

International Journal of Alzheimer's Disease

Year:

2011

Language:

english

File:

PDF, 1.78 MB

english, 2011

11

Histidines 13 and 14 in the Aβ sequence are targets for inhibition of Alzheimer's disease Aβ ion channel and cytotoxicity

DÍAZ, JUAN CARLOS, LINNEHAN, JOHN, POLLARD, HARVEY, ARISPE, NELSON

Journal:

Biological Research

Year:

2006

Language:

english

File:

PDF, 1.86 MB

english, 2006

12

The Small Heat Shock Proteins, HSPB1 and HSPB6, Have the Ability to Get Inserted into Lipid Membranes

De Maio, Antonio, Cauvi, David M., Capone, Ricardo F., Arispe, Nelson, Boelens, Wilbert

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 45 KB

english, 2019

13

The Antihypertensive Calcium Channel Blocker Nitrendipine Displays a Cytotoxic Effect on Neuroblastoma Cells, Which is Independent of Binding to L-Type Voltage-Gated Calcium Channels

De Maio, Antonio, Rivera, Isabel, Cauvi, David M., Arispe, Nelson

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 48 KB

english, 2018

14

Polyhistidine Peptide Inhibitor of the Aβ Calcium Channel Potently Blocks the Aβ-Induced Calcium Response in Cells. Theoretical Modeling Suggests a Cooperative Binding Process

Arispe, Nelson, Diaz, Juan, Durell, Stewart R., Shafrir, Yinon, Guy, H. Robert

Journal:

Year:

2010

Language:

english

File:

PDF, 3.43 MB

english, 2010

15

Aβ ion channels. Prospects for treating Alzheimer's disease with Aβ channel blockers

Nelson Arispe, Juan C. Diaz, Olga Simakova

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2007

Language:

english

File:

PDF, 1.48 MB

english, 2007

16

The Ability of Amyloid β-Protein [AβP (1–40)] to Form Ca2+ Channels Provides a Mechanism for Neuronal Death in Alzheimer's Disease

NELSON ARISPE, HARVEY B. POLLARD, EDUARDO ROJAS

Journal:

Annals of the New York Academy of Sciences

Year:

1994

Language:

english

File:

PDF, 530 KB

english, 1994

17

Alzheimer Disease Amyloid β Protein Forms Calcium Channels in Bilayer Membranes: Blockade by Tromethamine and Aluminum

Nelson Arispe, Eduardo Rojas and Harvey B. Pollard

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.04 MB

english, 1993

18

Modulation of Amyloid Peptide Oligomerization and Toxicity by Extracellular Hsp70

De Maio, Antonio, Rivera, Isabel, Cauvi, David M., Arispe, Nelson

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 44 KB

english, 2017

19

Calcium-independent K+-selective channel from chromaffin granule membranes

Nelson Arispe, Harvey B. Pollard, Eduardo Rojas

Journal:

Journal of Membrane Biology

Year:

1992

Language:

english

File:

PDF, 1.06 MB

english, 1992

20

Early and Late Cytotoxic Effects of External Application of the Alzheimer's Aβ Result from the Initial Formation and Function of Aβ Ion Channels †

Simakova, Olga, Arispe, Nelson J.

Journal:

Year:

2006

Language:

english

File:

PDF, 576 KB

english, 2006

21

Human and Bacterium Hsp70 Interacts Differently with Lipid Membranes

Lopez, Victor, Cauvi, David M., Arispe, Nelson, De Maio, Antonio

Journal:

Biophysical Journal

Year:

2016

Language:

english

File:

PDF, 52 KB

english, 2016

22

Elucidation of Ca2+ Influx through Alzheimer's Aβ Channels in the Aβ-Induced Cellular Ca2+ Response

Arispe, Nelson J.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

23

The HSP70 Interaction with Phosphatidyl Serine on Membranes is the Initial Step its Release Into the Extracellular Medium

Okerblom, Jonathan, Williams, Michael R., Cauvi, David M., Schlamadinger, Diana, Kim, Judy, Arispe, Nelson, De Maio, Antonio

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 37 KB

english, 2012

24

Calcium channel blockers commonly used as antihypertension agents augment the deleterious effect of beta-amyloid peptides on cells

Lin, Ho-pi, Knight, Brandon, Williams, Michael R., Cauvi, David, Bello, Ivan, Salerno, Milena, DeMaio, Antonio, Arispe, Nelson

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

25

Models of membrane-bound Alzheimer's Abeta peptide assemblies

Yinon Shafrir, Stewart Durell, Nelson Arispe, H. Robert Guy

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2010

Language:

english

File:

PDF, 659 KB

english, 2010

26

Aggregation of liposomes induced by the toxic peptides Alzheimer’s Aβs, human amylin and prion (106–126): facilitation by membrane-bound GM1 ganglioside

Boris Kurganov, Michael Doh, Nelson Arispe

Journal:

Year:

2004

Language:

english

File:

PDF, 605 KB

english, 2004

27

Polyhistidine Peptide Inhibitor of the Aβ Calcium Channel Potently Blocks the Aβ-Induced Calcium Response in Cells

Arispe, Nelson, Durell, Stewart R., Shafrir, Yinon, Guy, H.R.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 41 KB

english, 2010

28

Appointments.

Okerblom, Jonathan, Williams, Michael R., Cauvi, David M., Schlamadinger, Diana, Kim, Judy, Arispe, Nelson, De Maio, Antonio

Journal:

Year:

1887

Language:

english

File:

PDF, 194 KB

english, 1887

29

HSP70 Associates with Phosphatidylserine Membranes via the Peptide Binding Domain

De Maio, Antonio, Armijo, Gabrielle, Lopez, Victor, Gonzales, Derek, Okerblom, Jonathan, Arispe, Nelson, Cauvi, David M.

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 85 KB

english, 2014

30

Phosphatidyl-Serine-Positive Cells with High Sensitivity to the Alzheimer's Disease Aβ Peptides Display Distinctive Mitochondrial Characteristics

Simakova, Olga, Arispe, Nelson J.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 42 KB

english, 2012

31

Efficiency of Histidine-Associating Compounds for Blocking the Alzheimer's Aβ Channel Activity and Cytotoxicity

Arispe, Nelson, Diaz, Juan Carlos, Flora, Michael

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 378 KB

english, 2008

32

Interaction of heat shock protein 70 with membranes depends on the lipid environment

Armijo, Gabrielle, Okerblom, Jonathan, Cauvi, David M., Lopez, Victor, Schlamadinger, Diana E., Kim, Judy, Arispe, Nelson, De Maio, Antonio

Journal:

Cell Stress and Chaperones

Year:

2014

Language:

english

File:

PDF, 946 KB

english, 2014

33

Insertion of Hsp70 into Membranes is Mediated by Negative-Charged Phospholipids and Modulated by the Fluidity of the Bilayer

De Maio, Antonio, Armijo, Gabrielle, Okerblom, Jonathan, Cauvi, David M., Arispe, Nelson

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 53 KB

english, 2013

34

Insertion of Hsp70 Into Membranes Correlates With the Flipping of Phosphatidlyserine Across the Lipid Bilayer

De Maio, Antonio, Okerblom, Jonathan, Cauvi, David M., Vega, Virginia L., Arispe, Nelson

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 54 KB

english, 2010

35

A New Hypothesis for the Mechanism of Amyloid Toxicity, Based on the Calcium Channel Activity of Amyloid β Protein (AβP) in Phospholipid Bilayer Membranes

HARVEY B. POLLARD, EDUARDO ROJAS, NELSON ARISPE

Journal:

Annals of the New York Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 187 KB

english, 1993

36

Calcium Channel Blockers used as Anti-Hypertension Agents Affect the Toxicity of Aβ Peptides on Neurons

Arispe, Nelson, Williams, Michael R., Rivera, Isabel, Lin, Ho-pi, Cauvi, David M., De Maio, Antonio

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 43 KB

english, 2014

37

Modulation of Alzheimer's amyloid β peptide oligomerization and toxicity by extracellular Hsp70

Rivera, Isabel, Capone, Ricardo, Cauvi, David M., Arispe, Nelson, De Maio, Antonio

Journal:

Cell Stress and Chaperones

Year:

2017

Language:

english

File:

PDF, 1.61 MB

english, 2017

38

Differential blockage of two types of potassium channels in the crab giant axon

Bernat Soria, Nelson Arispe, M. Emilia Quinta-Ferreira, Eduardo Rojas

Journal:

Journal of Membrane Biology

Year:

1985

Language:

english

File:

PDF, 744 KB

english, 1985

39

Single-cell screening of cytosolic [Ca2+] reveals cell-selective action by the Alzheimer’s Aβ peptide ion channel

Lin, Hopi, Arispe, Nelson J.

Journal:

Cell Stress and Chaperones

Year:

2015

Language:

english

File:

PDF, 2.23 MB

english, 2015

40

Nitrendipine, an antihypertensive alpha calcium channel blocker, is cytotoxic to neuroblastoma cells

Rivera, Isabel, Cauvi, David M., Arispe, Nelson, De Maio, Antonio

Journal:

Molecular & Cellular Toxicology

Year:

2019

Language:

english

File:

PDF, 584 KB

english, 2019

41

Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity

Harvey B. Pollard, Nelson Arispe, Eduardo Rojas

Journal:

Cellular and Molecular Neurobiology

Year:

1995

Language:

english

File:

PDF, 1.20 MB

english, 1995

42

Antihypertensive Antagonists of L-Type Calcium Channel Exert Enhancement of Alzheimer's Aβ Peptides Effect on Cells

Knight, Brandon, Lin, Ho-pi, Arispe, Nelson J.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

43

Interactions With Imidazole Side Groups As A Mechanism To Block The Alzheimer'S Aβ Peptide-induced Intracellular Calcium Increase

Arispe, Nelson J., Diaz, Juan C., Flora, Michael

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 39 KB

english, 2009

44

β-amyloid Ca2+-channel hypothesis for neuronal death in Alzheimer Disease

Nelson Arispe, Harvey B. Pollard, Eduardo Rojas

Journal:

Molecular and Cellular Biochemistry

Year:

1994

Language:

english

File:

PDF, 565 KB

english, 1994

45

Zn2+Interaction with Alzheimer Amyloid β Protein Calcium Channels

Nelson Arispe, Harvey B. Pollard and Eduardo Rojas

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 448 KB

english, 1996

46

Giant Multilevel Cation Channels Formed by Alzheimer Disease Amyloid β-Protein [AβP-(1-40)] in Bilayer Membranes

Nelson Arispe, Harvey B. Pollard and Eduardo Rojas

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.09 MB

english, 1993

47

β-Amyloid in Alzheimer’s Disease

Dr Harvey B. Pollard,Eduardo Rojas,Nelson Arispe

Journal:

Year:

1994

Language:

english

File:

PDF, 961 KB

english, 1994

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